The Center for Preclinical Research (ZPF) is a central institution of the TUM School of Medicine and Health. We develop and establish research models for the treatment of diseases, such as in the fields of oncology (cancer research), cardiology, neurology, ophthalmology and orthopedics. These models are used to investigate new therapeutic strategies and diagnostic procedures for serious medical conditions.
Interdisciplinary Center for Cellular Therapies
TUMCells is a joint initiative of the Helmholtz Center Munich, the University Hospital rechts der Isar (MRI) and the TUM School of Medicine and Health. TUM is in charge of the facility and assumes the responsibilities of a pharmaceutical manufacturer, a pharmaceutical entrepreneur and sponsor for clinical trials. With our GMP manufacturing facility for ATMPs we are hoping to offer new perspectives for technical and therapeutic innovations, especially for academic institutions in the Munich region. We also aim to contribute to the structure of clinical research in an academic environment.
Our facility is designed to manufacture, test and release somatic cell therapies, gene transfer medicinal products and tissue engineering products. We offer the complete range of GMP services such as project consultation and development, the provision of plant capacity on a contract basis and the production of ATMPs.
The unit for Comparative Experimental Pathology (CEP) was established in 2016 by Dr. Katja Steiger and Prof. Wilko Weichert. It represents a new, interdisciplinary research platform that offers well-founded technical and scientific pathological expertise for clinically and experimentally active research groups at the Technical University of Munich as well as at the University Hospital rechts der Isar.
The CEP features an independent, fully equipped histological laboratory with state-of-the-art technology. Next to an embedding station, we have a full automatic coverslipper, both being used in a routine setting in our lab. Besides that, we provide different immunohistological platforms for standardized and automated immunohistochemistry. We are also equipped with four slide scanners, of which three are for high throughput scanning. Furthermore, we have added a state-of-the-art laser microdissection and a light-sheet fluorescence microscope to our equipment.
Die CEP Core Facility is currently being developed into a school-based core facility at the TUM School of Medicine and Health.
The Proteomics Core Unit at the University Hospital rechts der Isar is part of BayBioMS (Bayerisches Zentrum für Biomolekulare MassenSpektrometrie), the latest science and technology platform of TUM and MRI providing access to state-of-the-art proteomics tools and scientific expertise. Together with our collaborators at the TUM schools, the greater Munich area and across Germany, Europe and the world we push the frontiers of molecular research in all areas of the life sciences.
The Proteomics Core Unit provides competent scientific support for your proteomics project, from experimental design through data acquisition, bioinformatics analysis and data interpretation.
The Proteomics Core Unit is currently being developed into a school-based Core Unit at the TUM School of Medicine and Health.
The Prevention Center is divided into the three core labs "Human Physiology & Prevention Lab", "Molecular Physiology Lab" and the "Living Lab". The teaching and learning lab is also located there for the education of our students.
The Human Physiology & Prevention Lab is the core facility for all studies in which movement is either the main focus or is necessary to trigger certain effects. The equipment offers the opportunity to conduct complex musculoskeletal or physiological basic research in addition to traditional sports science research. The focus is on procedures in the key areas of performance physiology and cardiovascular diagnostics, biomechanics and human movement sciences, anthropometry and metabolism as well as neurocognitive and motor diagnostics.
Collected blood and tissue samples can be analyzed in the Molecular Physiology Lab or initially processed and evaluated at a partner institution (e.g. Helmholtz Center).
- Cell Analysis: The Core Facility Cell Analysis (CFCA) is a cytometry and imaging facility that provides a convenient and guided access to advanced cell analysis technologies and fosters the benefits of these resources to researchers in and around the TranslaTUM. Learn more
- PICTUM: The imaging core facility is an essential component to animal research at the TranslaTUM. Since the core facility is located within the animal facility, animals can be picked up from the holding rooms, scanned on the equipment, and returned while maintaining the high hygiene levels of the animal facility. Learn more
Multiple sclerosis (MS) is the most common inflammatory disease of the nervous system, typically occurring in young adulthood. Although significant progress has been made in understanding and treating the disease, as with many neurodegenerative diseases, therapeutic strategies for the chronic progressive phase of the disease are lacking. The “Center for Multiple Sclerosis and Neuroscience” will provide patients with inflammatory CNS diseases with the latest diagnostic and therapeutic options and will advance research in this area.
In the new building, we will unite neuroscientific research at the university to develop new strategies for the treatment of MS, as well as other neurodegenerative diseases, and then implement the application in humans. The close integration of clinical care structures, study outpatient clinics, clinical and basic research will create a “Center for Multiple Sclerosis and Neuroscience” that is unique in Europe.
The Center for Digital Medicine and Health (ZDMG) at the Technical University of Munich (TUM) aims to develop new and pioneering approaches in the fields of data science, AI and machine learning and to promote their translation into medical care and health sciences for the direct benefit of patients. The ZDMG will address fundamental challenges to AI in medical applications: Robustness, Security, Transparency, Privacy, and Data Quality Management. To this end, it will develop new and innovative AI approaches for machine learning without supervision and with multi-modal data, as well as for causal relationship discovery and inference. The translation of these approaches into innovative solutions for biomarker discovery and development of new diagnostic and therapeutic approaches is part of the core mission of the ZDMG.
A globally unique position results not only directly from the targeted questions and the excellence of the scientists involved, but also from the extraordinary opportunities provided by the location of the University Hospital rechts der Isar to translate research results into clinical practice for the direct benefit of patients. While other Data Science/KI initiatives in the field of medicine are limited to specific topics such as radiology, the ZDMG is characterized by its broad thematic focus on data-driven medicine. This creates a research center with national and international appeal.